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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Double-activation of mitochondrial permeability transition pore opening via calcium overload and reactive oxygen species for cancer therapy

Fig. 5

a Schematic description of the establishment of 4T1 tumor model and therapeutic outcome. b The relative tumor volume of mice in different groups after treatment. P values were calculated by one-way analysis (*p < 0.05, **p < 0.01, ***p < 0.001). Data were represented as mean ± SD (n = 6). c Tumor weight in different groups after treatment. P values were calculated by one-way analysis (*p < 0.05, **p < 0.01, ***p < 0.001). Data were represented as mean ± SD (n = 6). d H&E, TUNEL and Caspase 3 staining of tumor collected from mice after various treatments

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