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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Engineering defected 2D Pd/H-TiO2 nanosonosensitizers for hypoxia alleviation and enhanced sono-chemodynamic cancer nanotherapy

Fig. 5

Gene expression analysis of SDT and CDT treated C6 cells by RNA sequencing. a Volcano map presenting the downregulated and upregulated genes in Pd/H-TiO2-PEG + H2O2 + US treated C6 cells (p-adjust < 0.05, absolute fold-change cut off ≥ 1.5). b Clustering analysis of DEGs in treated and untreated C6 cells. c Heatmaps of DEGs associated with immune, apoptosis, tumor microenvironment, oxidative stress and glioma. d GO and e KEGG enrichment analyses of functions and signal pathways that the related DEGs participated in. f PPI network of the proteins encoded by DEGs

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