Fig. 1
From: Preclinical safety and hepatotoxicity evaluation of biomineralized copper sulfide nanoagents
Physicochemical characterization of BSA@Cu2−xS NPs. It is noted that “LNPs” stands for large-sized BSA@Cu2−xS NPs and “SNPs” for those with small-sizes. A TEM images for LNPs and SNPs. B The hydrodynamic sizes of both NPs in water, PBS and 10% FBS by DLS measurement. C XPS spectra for LNPs and SNPs. D UV–vis–NIR spectra of both NPs at different concentrations (equivalent to 5, 10, 20, 40, 80 μg/mL Cu). E Photothermal heating curves of both NPs at different concentrations under 1064 nm laser irradiation with a power density of 1 W/cm2. F Photothermal heating and natural cooling curve at a dose of 40 μg/mL (black line) and linear relationship between − lnθ (negative natural logarithm of the temperature driving force) and time in the cooling stage (blue line)