Fig. 6

Effects of PL, PL-exo and PL-exo-ALN on MPS-induced bone mass loss in vivo. A 2D and 3D reconstructive μ-CT images in the distal femurs of five groups. B Quantification of the bone mineral density (BMD), trabecular bone volume fraction (BV/TV), trabecular number (Tb.N), trabecular thickness (Tb.Th) and trabecular separation (Tb.Sp) by CTAn of five groups. C Images of dynamic bone formation with different treatments were monitored the fluorochrome labeling of five groups (scale bar: 300 μm). D Bone minerals of different groups were examined by Von Kossa staining of five groups. All results are presented as the means ± SDs, ^*P < 0.05, ^**P < 0.01