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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: Nanozyme-natural enzymes cascade catalyze cholesterol consumption and reverse cancer multidrug resistance

Fig. 3

Research on apoptosis and protein. A Effects of different preparations on mitochondrial membrane potential of MCF-7/ADR cells. J-aggregates: Red fluorescent; J-1 monomer: Green fluorescence. B Results of DOX@MOF-COD@CS nanoparticles producing reactive oxygen species in MCF-7/ADR cell. DCFH was used as the probe. DCFH oxidation forms DCF: green fluorescence. C Annexin V-FITC/PI double staining method to determine the effects of different preparations on the cell apoptosis. D Western blot test and the related protein expression of COX-2 and BCL-XL. Data are presented as mean ± SD (n = 3), **P < 0.01, ***P < 0.001

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