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Fig. 1 | Journal of Nanobiotechnology

Fig. 1

From: Inflammation-sensing catalase-mimicking nanozymes alleviate acute kidney injury via reversing local oxidative stress

Fig. 1

Schematic illustration showing preparation and mode of action of PTC-M A Synthesis of PTC-M, B Mechanism of action of PTC-M (1) intravenous injection of PTC-M (2) the injected PTC-M circulates in blood and accumulates at the inflammation site (3) the destabilization of PTC-M due to the intrinsic ROS present at the inflammation site (4) release of the loaded dMn3O4 at the inflammation site (5) the released dMn3O4 catalyzes the ROS scavenging leading to (6) reduction in inflammation, apoptosis and fibrosis (7) alleviation of kidney damage and (8) improved kidney functions

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