Fig. 5From: NOX4 blockade suppresses titanium nanoparticle-induced bone destruction via activation of the Nrf2 signaling pathwayNOX4 is involved in wear particle-induced PPO. A Images of clinical tissues obtained from patients with primary TJA and revision TJA. B Representative images of immunofluorescence staining of NOX4-positive cells and quantification. Scale bars, 100 µm. C Protein levels of NOX4 in different samples. *p < 0.05, **p < 0.01Back to article page