Fig. 1
From: Monitoring in vivo behavior of size-dependent fluorescent particles as a model fine dust
Synthesis and characterization of CSPM. a Schematic illustration of the synthesis of CSPMs with different particle sizes and their in vivo biodistribution imaging studies. b A representative FE-SEM image (scale bar = 100 nm) and HR-TEM image (the inset, scale bar = 200 nm) of the synthesized CSPM0.1. c Size distribution analysis of the synthesized CSPM0.1. d Surface zeta potentials of silica particulate matter (SPM) without dye-doping and CSPM0.1. e Fluorescence spectra (excitation and emission scan modes) of CSPM0.1. f Fluorescence intensity profiles of CSPM0.1, Cy7-APTES, and Cy7 with time. g In vitro dye release profiles of CSPM0.1. Fluorescence intensity linearity in h in vitro and i in vivo environments for CSPM0.1. CSPM0.1 was subcutaneously injected into the mouse abdomen at different concentrations