Fig. 6

Effect of HPP@Cu gel on macrophage phenotype. a Immunofluorescence analysis of markers of M1 (iNOS, green) and M2 (CD206, red) on macrophages after different treatments. b Corresponding to a, the mean fluorescence intensity of iNOS was quantified by ImageJ. c Corresponding to a, the mean fluorescence intensity of CD206 was quantified by ImageJ. d Flow cytometry analysis of the percentage of M2 in the macrophage population. In b, c, data represent means ± SD, n = 3. **p < 0.01, ##p < 0.01, and &&p < 0.01. NS means not significant