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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: Multifunctional thermo-sensitive hydrogel for modulating the microenvironment in Osteoarthritis by polarizing macrophages and scavenging RONS

Fig. 7

Histological analysis after treatment in vivo. a Schematic illustration of the establishment and treatment schedule of MIA-induced OA rats. b Pelletier score analysis according macroscopic appearance, and OARSI score analysis according H&E staining and Safranin O staining. Data represent means ± SD, n = 3. &p < 0.05. **p < 0.01, and ##p < 0.01. NS means not significant. c Macroscopic appearance of joints after treatment. d H&E staining and Safranin O staining of joints after treatment. Scale bars = 50 μm

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