Fig. 8From: Multifunctional thermo-sensitive hydrogel for modulating the microenvironment in Osteoarthritis by polarizing macrophages and scavenging RONSa Levels of ROS in joint tissue homogenate. b Levels of RNS in joint tissue homogenate. c Levels of IL-1β in joint tissue homogenates. d Levels of TNF-α in joint tissue homogenates. e Levels of IL-10 in joint tissue homogenates. f Immunofluorescence staining of iNOS (M1 marker, red) and CD206 (M2 marker, green) of synovial tissue. g Liver function indicators levels and kidney function indicators levels of serum after treatment. In a–e, and g, data represent means ± SD, n = 3. *p < 0.05, #p < 0.05. **p < 0.01, ##p < 0.01, and &&p < 0.01. NS means not significantBack to article page