Fig. 2

V9302/MoS₂-V9302 inhibits glutamine metabolism and improves CD8⁺ cells in the tumor core. Cytotoxicity of MoS₂-V9302 in 4T1 cells incubated for a 48 h and b 72 h. c The glutamine uptake of 4T1 tumor cells treated by V9302/MoS₂-V9302. d Immunohistochemistry of CD8 (red) in tumor sections. Nuclei were stained with DAPI (blue). The tumor was divided into Edge (< 500 μm from tumor margin) and core (> 500 μm) regions by a yellow solid line. Scale bars: 50 μm. e CD8⁺ cells were counted and calculated from 3 fields of view. **P < 0.01