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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Brain-targeted heptapeptide-loaded exosomes attenuated ischemia–reperfusion injury by promoting the transfer of healthy mitochondria from astrocytes to neurons

Fig. 2

Characterization of EXO and EXO-Hep. A Western blotting analysis of exosomes surface markers. EXO was isolated and collected by centrifuging culture medium of RAW264.7 cells. The bottom sediment was collected to obtain EXO and the residual supernatant containing no exosomes was selected as the negative control. Hep was loaded into EXO using sonication and EXO-Hep were obtained by a series of centrifugations. B Size and morphology of EXO and EXO-Hep observed by TEM. Scale bar: 100 nm. C Particle size distribution of EXO and EXO-Hep measured by DLS

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