Fig. 11
From: Application of lipid nanovesicle drug delivery system in cancer immunotherapy
Reprint with permission from [114]
a Schematic illustration of the trimodal anticancer therapy by using M1CCD. b TEM image of M1CCD. Scale bar: 200 nm. c Production levels of IL-6 and TNF-α in M2 macrophages assayed by ELISA after different treatments for 24 h. d Tumor growth curves for all treated groups and (e) survival rates of tumor-bearing mice receiving different treatments in vivo. f Time-dependent ratios of the M1 phenotype to the M2 phenotype in tumor tissues after treatment with M1CCD.