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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Construction of gastric cancer patient-derived organoids and their utilization in a comparative study of clinically used paclitaxel nanoformulations

Fig. 2

Genomic comparisons of GC PDOs with the primary tumor from patient GC3. A Heatmap showing CNVs in the primary tumor and the corresponding GC PDOs. The columns represent genomic positions from chromosomes 1 to 22, and the colors in the plot correspond to the estimated log2 copy ratios of the genomic regions. B CNVs heatmap of GC driver genes in the primary tumor and the corresponding GC PDOs. Gene copy numbers are transformed as log2 ratios per gene. C Heatmap showing gene mutation variations in the most frequently mutated GC genes. SNV: single-nucleotide variant. D Bar graphs showing the point mutation types found in the primary tumor and in the corresponding GC PDOs.

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