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Fig. 4 | Journal of Nanobiotechnology

Fig. 4

From: Construction of gastric cancer patient-derived organoids and their utilization in a comparative study of clinically used paclitaxel nanoformulations

Fig. 4

Distinct cytotoxic effects of PTX nanoformulations on GC1 PDOs at the transcriptome and cellular levels. A Transcriptome analysis of GC1 PDOs after treatment with Albu-PTX or Lipo-PTX. Differential gene cluster analyses are shown as heatmap. B KEGG pathway analysis of GC1 after treatment with Albu-PTX or Lipo-PTX. C GSEA of GC1 for gene sets that were changed in the Lipo-PTX treatment group versus the Albu-PTX treatment group. D Live-Dead staining analysis of GC1 PDOs after treatment with Albu-PTX or Lipo-PTX. Green: live cells; red: dead cells. Scale bar, 50 μm

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Journal of Nanobiotechnology

ISSN: 1477-3155

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