Fig. 6

A In vivo fluorescence images of 4T1 tumor-bearing mice that were intravenously injected with Alg@CaP/I at different time points and B ex vivo fluorescence images of major organs and tumors at 24 h post injection. C Histogram analysis of relative average radiant efficiency of liver, lungs, and tumor. D TUNEL-stained tumor slices collected from 4T1 tumor-bearing mice after treatments for 15 days. The scale bar was 50 μm. E Blood analysis of mice at 15 days after various treatments. F Relative volume changes and G mice body weight changes in different groups. Data are mean ± SD, n = 5; *P < 0.05, **P < 0.01, and ***P < 0.001 vs. control