Fig. 4

In vivo antitumor study. A Schematic diagram of MCF-7 tumor model. B Images of MCF-7 tumor-bearing mice in different treatment groups. C Body weight (n = 6) and D Tumor volume of each mouse in each group (n = 6). E Amplifying H&E and TUNEL staining assay of the tumor from the mice in all groups after treatment for 21 days. F Bar graph of quantitation of TUNEL positive cells. Scale bar, 100 μm. Data are presented as the mean ± s.d. (n ≥ 3). *P < 0.05; **P < 0.01; ***P < 0.001