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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: Microvesicle-camouflaged biomimetic nanoparticles encapsulating a metal-organic framework for targeted rheumatoid arthritis therapy

Fig. 6

Therapeutic effect of methotrexate (MTX)-based formulations in rats with collagen-induced arthritis (CIA). A Schematic illustration of the treatment process. B–E Changes in B mean articular score, C body weight, D ankle diameter, and E paw volume over time. F Photographs of hind limbs of CIA rats treated with various MTX formulations. Data are shown as mean ± SD (n = 3). FPD: 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[folate (polyethylene glycol)-2000; MV: microvesicle; ZIF-8: zeolitic imidazolate framework-8

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Journal of Nanobiotechnology

ISSN: 1477-3155

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