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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: Microvesicle-camouflaged biomimetic nanoparticles encapsulating a metal-organic framework for targeted rheumatoid arthritis therapy

Fig. 7

Micro-computed tomography of the hind limbs of rats with collagen-induced arthritis after treatment with different formulations. A Representative 3D reconstructed images from each treatment group. B Bone mineral density (BMD). C Ratio of bone surface area to bone volume (BS/BV). D Ratio of bone volume to tissue volume (BV/TV). E Trabecular number (Tb.N). F Trabecular separation (Tb.Sp). G Trabecular thickness (Tb.Th). Data are shown as mean ± SD (n = 3). *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 vs. saline group. FPD: 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[folate (polyethylene glycol)-2000; MTX: methotrexate; MV: microvesicle; ZIF-8: zeolitic imidazolate framework-8

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Journal of Nanobiotechnology

ISSN: 1477-3155

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