Fig. 5
ZnPc-EVs accumulate in tumors following intravenous administration. C57BL/6-albino mice were inoculated with 0.5 × 106 MC38 cells in the right flank. At 7 days after inoculation, when tumors were established (~ 125 mm3), the mice were intravenously injected with the ZnPc-EVs in the tail vein. a The presence of ZnPc in the tumors was measured over time by fluorescence spectrometry using the IVIS fluorescence spectrometer. b Representative IVIS images of the mice with a fluorescence overlay of the 700 nm channel at 51 h after administration are shown. (mean±SEM; n=4)