Fig. 5From: Bioimaging guided pharmaceutical evaluations of nanomedicines for clinical translationsSize-dependent intratumoral accumulation of NMs. A Left: schematic illustration of ZCIS QDs and hydrodynamic diameters distribution of ZCIS NMs-25 and ZCIS NMs-80. Right: in vivo multispectral optical tomography (MSOT) images of tumors (indicated with white arrows) in mice obtained at different time points after i.v. injection of ZCIS NMs-25 and ZCIS NMs-80. B In vivo MRI images of the tumor bearing mice obtained at 48Â h p.i. (arrows indicate tumors). C MSOT signal increase in the tumor at various times p.i. Reproduced with permission from [159]. Copyright 2016, American Chemical SocietyBack to article page