From: A novel nanobody-heavy chain antibody against Angiopoietin-like protein 3 reduces plasma lipids and relieves nonalcoholic fatty liver disease
Parameter
Protein
hANGPTL3 (S17-K170)
hANGPTL3 (S17-E460)
mANGPTL3 (S17-T206)
mANGPTL3 (S17-T455)
C44-Fc, IC50 (nM)
1.6
4.6
3.6
5.4
Evinacumab, IC50 (nM)
1.7
1.8
3.7
Control Ab, IC50 (nM)
NB