Fig. 6
Assessment of NO generation from PCM-MSN@LA in the cardiomyocytes with or without LIFU in vitro. a The expression of iNOS and eNOS in LPS-incubated cardiomyocytes from 5 min to 24 h. b, c The quantitative analyses of iNOS and eNOS expression (n = 6). Data were presented as mean ± SD. *P < 0.05; **P < 0.01. d Relative nitrite concentration from different doses of PCM-MSN@LA in cardiomyocytes with or without LPS (n = 6), Data were presented as mean ± SD. *P < 0.05; **P < 0.01. e Confocal images of cardiomyocytes stained by DAF-FM DA following 75 μg mL−1 PCM-MSN@LA irradiated with LIFU over time (scale bar = 100 μm)