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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: Dual-functional alginate and collagen–based injectable hydrogel for the treatment of cancer and its metastasis

Fig. 7

Role of TRG as a cancer therapeutic carrier for immunotherapy. On the 7th day after CT-26 tumor implantation, the mice were i.t. injected with TRGs containing either PBS, poly I:C, stimulator of interferon genes ligand (STING L), anti-PD-1 antibody (α-PD-1), or anti-PD-L1 antibody (α-PD-L1) under NIR laser irradiation (1.5 W/cm2, 5 min). A iRFP imaging in CT-26 tumor-bearing mice on the 20th day after tumor injection (n = 5). B Tumor growth curves of CT-26 mice (n = 6, significance was determined by the log-rank test, mean ± SEM **p < 0.01). C The survival rates of mice were monitored during the first and second challenges (n = 5 per group). D iRFP fluorescence images and E photographs of metastatic lung cancer 10 days after the second challenge (n = 5)

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