Fig. 7

In vivo pharmacokinetics and anti-tumor efficacy. Plasma drug curves after oral administration of A Taxol^®, PTX@NPs, PTX@GLNPs, PTX@GCA-NPs, PTX@GCA-NPs + TCA (p.o.). B PTX@GCA-NPs, PTX@GCA-NPs + CHE (s.c.) at a PTX dose of 10 mg/kg. n = 3. C The changes of tumor volume after treatments. D Tumor weights. E Tumor photos at days 19 post-inoculation. GCA-NPs (5) and GCA-NPs (10) refer to 5 mg/kg and 10 mg/kg dosage of PTX, respectively. F Representative images of TUNEL assay (magnification: 200 ×). Data for C, D, F is presented as mean ± SEM, n = 6, ***P < 0.001, **P < 0.01, *P < 0.05