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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Targeted delivery of fat extract by platelet membrane-cloaked nanocarriers for the treatment of ischemic stroke

Fig. 2

Effects of RGD-PLT@PLGA-FE on HUVECs in Vitro. A The overlap imaging of HUVECs treated with DiO labeled PLGA, PLT@PLGA and RGD-PLT@PLGA (green). Scale Bar = 100 μm. B, C Flow cytometry showed the average fluorescent intensity of HUVECs incubated with DiO labeled PLGA, PLT@PLGA and RGD-PLT@PLGA. n = 3/group. D Tube formation of HUVECs that treated with medium, FE, PLGA, PLGA-FE, PLT@PLGA, PLT@PLGA-FE, RGD-PLT@PLGA, RGD-PLT@PLGA-FE. Scale Bar = 500 μm. E Migration of HUVECs that treated with medium, FE, PLGA, PLGA-FE, PLT@PLGA, PLT@PLGA-FE, RGD-PLT@PLGA, RGD-PLT@PLGA-FE. Scale Bar = 500 μm. F Quantitative analysis of the number of the branches of HUVECs that treated with medium, FE, PLGA, PLGA-FE, PLT@PLGA, PLT@PLGA-FE, RGD-PLT@PLGA, RGD-PLT@PLGA-FE. n = 3/group. G. Quantitative analysis of the changes in scratch areas that treated with medium, FE, PLGA, PLGA-FE, PLT@PLGA, PLT@PLGA-FE, RGD-PLT@PLGA, RGD-PLT@PLGA-FE. n = 3/group. Data presented as mean ± SD. *p < 0.05, **p < 0.01

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