Fig. 3

In vivo fluorescence imaging of stroke mice treated with RGD-PLT@PLGA. A EX vivo fluorescence imaging of heart, liver, spleen, lung and kidney of mice that treated with 10% sucrose, PLGA only, PLT@PLGA and RGD-PLT@PLGA. B Quantitative analysis of the average DiD fluorescence signal intensities in the brain that treated with 10% sucrose, PLGA, PLT@PLGA and RGD-PLT@PLGA. n = 3/group. C Quantitative analysis of the average DiD fluorescence signal intensity per gram tissue after injection with RGD-PLT@PLGA over time (24 h, 48 h and 72 h). n = 3/group. D. Quantitative analysis of the relative signal per organ after injection with RGD-PLT@PLGA over time (24 h, 48 h and 72 h). n = 3/group. Data presented as mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001