Fig. 6

Changes in blood flow after ischemic stroke by laser sparkle imaging. A The pattern diagram of laser speckle imaging. Blood flow was calculated from the area indicated by the black circle. B The laser sparkle imaging of baseline, before reperfusion, after reperfusion and 14 days after stroke of mice treated with sham, 10% sucrose, FE, PLGA-FE, PLT@PLGA-FE, RGD-PLT@PLGA and RGD-PLT@PLGA-FE. C Quantitative analysis of the blood flow of seven groups including sham, 10% sucrose, FE, PLGA-FE, PLT@PLGA-FE, RGD-PLT@PLGA and RGD-PLT@PLGA-FE treated mice. &&&, RGD-PLT@PLGA-FE vs 10% Sucrose. **, RGD-PLT@PLGA-FE vs FE. ##, RGD-PLT@PLGA-FE vs RGD-PLT@PLGA. n = 8, 8, 7, 7, 6, 8, 7 (from left to right). Data presented as mean ± SD. **, ##p < 0.01, &&&p < 0.001