Fig. 4
Cell viability assay. Viability of A Nthy-ori 3-1 and B 8505C cells treated with different concentrations of iRGD-Exos (0–1000 μg/mL) for 24 h. C 8505C and D Hth7 cells were incubated with control medium, iRGD-Exos, Na131I (3.7 MBq/well), blank-Exos-131I, iRGD-Exos-131I, Dox, Dox@iRGD-Exos, or Dox@iRGD-Exos-131I (15 μg/mL Dox) at 24 h at the same dose of radioactivity (3.7 MBq/well). A CCK-8 assay was used to assess cell viability in each group. NS (not significant) indicates P > 0.05 compared to the control group; *P < 0.05; **P < 0.01; $ indicates P < 0.01 compared to the other groups; & indicates P < 0.001 compared to the other groups