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Fig.4 | Journal of Nanobiotechnology

Fig.4

From: Ultrasound-assisted brain delivery of nanomedicines for brain tumor therapy: advance and prospect

Fig.4

A FUS combined with PFCNDs induced BBB opening with acoustic pressure of 0.5 MPa, 1.0 MPa and 1.5 MPa. ac EB staining of brain; dg enlarged (× 40) corresponding black rectangle region in H&E stain; gi enlarged (× 200) corresponding black rectangle region in H&E stain. B Distribution pattern of EB extravasation when nanodroplets or MBs was used as mediating agent combined with FUS [45]

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