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Table 2 The carriers of UABD nanomedicines

From: Ultrasound-assisted brain delivery of nanomedicines for brain tumor therapy: advance and prospect

Types Materials Sizes (nm) Drugs Refs
Lipid-based PEG-PEI 100 RVG-R9& pDNA [12]
Hydrogenated soybean L-α-phosphatidylcholine&
cholesterol&
DSPE-PEG2000;
116.1 ± 30.3 DOX&AP-1 [74]
DSPE-PEG2000& DPPG&
DSPC& PEG4000
50–200 MTX [75]
DPPG 180–200 Cisplatin [76]
DPPC; DSPE-PEG2000-amine; Chol 105 Gene [54]
Polymer-based PEG‑b‑PMNT&PEG‑b‑PCMS 40 RNPs [77]
PLGA& DPPC  ≤ 60 siRNA [78]
SPAnH  ~ 10–20 BCNU [79]
PEBCA 274 dye [80]
PEG-PLA 105.4 ± 33.0;
106.7 ± 33.9;
129.0 ± 41.7
Coumarin 6;
DiR;
Fe3O4
[81]
Biomacromolecule-based Albumin Paclitaxel [47]
BPN gene vectors  ~ 50 Cy5-labeled plasmid DNA [82]
Albumin 100 ~ 200 Ultrasmall iron oxide [56]
Inorganic-based AuNPs  ~ 10 Cisplatin [83]
TiO2 210 ± 23 TMZ [84]