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Fig. 8 | Journal of Nanobiotechnology

Fig. 8

From: Recent development of contrast agents for magnetic resonance and multimodal imaging of glioblastoma

Fig. 8

Mn-based contrast agents. a TEM images of HA-MnO2 NPs. b Cell viability of C6 glioma cells after incubation with HA-MnO2 NPs and HA-PAH-MnO2 NPs at varying Mn concentrations. c In vivo T1WI after intravenous injection of HA-PAH-MnO2 NPs and HA-MnO2 NPs [reprinted with permission from [95]; copyright (2019) John Wiley and Sons, Inc.]. d Schematic diagram of the synthesis of RGD-Au–Mn DENPs. e The T1WI of the C6 orthotopic glioma tumor before and after the non-targeted Au–Mn DENPs or targeted RGD-Au–Mn DENPs. The CT images (f) and quantitative CT values (g) of the C6 orthotopic glioma tumor before and after the non-targeted Au–Mn DENPs or targeted RGD-Au–Mn DENPs were intravenously injected, respectively [reprinted with permission from [141]; copyright (2019) Royal Society of Chemistry]

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