Fig. 5
From: Dual-binding nanoparticles improve the killing effect of T cells on solid tumor
Immune responses based on OT-I T cells reinfusion therapy. Flow cytometry analysis of CD8 + T cells proportion in blood (A), spleens (B) and tumors (C) by Flowjo 10, n = 5. Granzyme B (D) and IFN-γ (E) content in spleens, lymph nodes and tumors detected by Elisa assay, n = 5. F Immunofluorescence images of CD8 + T cells and IFN-γ in tumor tissues. Scale bar, 100 μm. Statistical analyses were carried out by Prism graphpad 8.0. All error bars are expressed as ± SD. Comparisons between two or several groups were analyzed using unpaired Student’s t-test, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001