Fig. 4

a The viability of THLE-3 cells treated with FePt, LFePt, and pLFePt. The viability of (b) MDA-MB-231 and c 4T1 cells treated with FePt, LFePt, pLFePt, and pLFePt-GOx. d CLSM images of Calcein-AM and propidium iodide (PI) co-stained MDA-MB-231 cells with different treatments. e The viability of MDA-MB-231 cells treated with pLFePt-GOx under different concentrations of glucose (n = 5, mean ± SD, *Means p < 0.05, **Means p < 0.01, ***Means p < 0.001). f CLSM images of MDA-MB-231 cells stained with JC-1 after treatment with different samples. g Western blot analysis of the protein expression of Bcl-2, Bax, GPX4, AMPK, and p-AMPK after different samples treatment. The cropped images originated from the white rectangles in Additional file 1: Fig. S11