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Fig. 1 | Journal of Nanobiotechnology

Fig. 1

From: An enhanced antioxidant strategy of astaxanthin encapsulated in ROS-responsive nanoparticles for combating cisplatin-induced ototoxicity

Fig. 1

Physicochemical characterization of ATX-PPS-NP and in vitro ROS-responsive release. A The preparation of ATX-PPS-NP. B Gaussian distribution of the ATX-PPS-NP. C–D In 4 °C or 37 °C environments, the remaining percentages of ATX alone or encapsulated in PPS-NP in dark or light conditions within 21 days. *p < 0.05, **p < 0.01, ***p < 0.001 vs ATX dark, ###p < 0.001 vs ATX light. E In vitro Nile red (NiRe) release from NiRe-PPS-NP in various concentrations of H2O2 solutions. F In vitro release of NiRe with intermittent exposure (OFF/ON cycles every other day) to 500 mM H2O2 solution. G Representative TEM images of ATX-PPS-NP in control and various oxidation groups

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