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Scheme 1 | Journal of Nanobiotechnology

Scheme 1

From: Lipid-coated albumin-paclitaxel nanoparticles loaded with sorcin-siRNA reverse cancer chemoresistance via restoring intracellular calcium ion homeostasis

Scheme 1

Schematic illustrations of the construction of lipid-coated albumin nanoparticles with PTX and SRI-siRNA (LANP-PTX-siSRI) and the depiction of LANP-PTX-siSRI work on revising chemoresistance. Lipid consists of DOPE/DOTAP. Ca++, calcium ions; DOPE, dioleoylphosphatidylethanolamine; DOTAP, 1,2-dioleoyl-3-trimethyl-ammonium-propane; P-gp, glycoprotein; SRI, sorcin; siSRI, SRI-siRNA

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