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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Traditional Chinese medicine active ingredients-based selenium nanoparticles regulate antioxidant selenoproteins for spinal cord injury treatment

Fig. 2

Cellular uptake and intracellular trafficking of TSIIA@SeNPs-APS. A Fluorescence intensity of couramin-6-labelled TSIIA@SeNPs-APS in PC12 cells for different time assessed by flow cytometry. B Cellular uptake of couramin-6-labelled TSIIA@SeNPs-APS in PC12 cells after pretreated with different inhibitors. Significant difference between control group and other groups is indicated by *P < 0.05, **P < 0.01, ***P < 0.001. C Intracellular trafficking of couramin-6-labelled TSIIA@SeNPs-APS in PC12 cells, which were stained by DAPI (blue, nucleus) and Lysotracker (red, lysosome), and visualized using a fluorescence microscopy. The scale bar is 10 nm. D Schematic illustration of cellular uptake and intracellular trafficking of TSIIA@SeNPs-APS

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