Fig. 2

Cell viability in vitro. Cellular uptake of the nanosystem by C1498 cells and RAW247.6 cells analyzed by (A) flow cytometry and (B) CLSM. Scale bar, 40 μm. C Cytotoxicity of different treatments (n = 3). D ROS generation in C1498 cells with different treatments. E Apoptosis assay of C1498 cells with different treatments. F Statistical analysis of (E). Data are shown as mean ± SD. P values were calculated by Student's t-test, ***p < 0.001