Fig. 4

Anti-tumor efficacy in AML model. A Establishment of the AML model and treatment scheme. B Bioluminescence images of the mice with different treatments. C Flow cytometry analysis of the number of C1498 cells in bone marrow (n = 3). D Statistical analysis of (C). E Bioluminescence intensity of treated mice on day 22 (n = 3). F Survival curves of mice (n = 6). Data are shown as mean ± SD. P values were calculated by Student's t-test (D, E) and log-rank (Mantel-Cox) test (F), *p < 0.05, **p < 0.01, ***p < 0.001