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Fig. 8 | Journal of Nanobiotechnology

Fig. 8

From: Photoluminescent carbon dots (PCDs) from sour apple: a biocompatible nanomaterial for preventing UHMWPE wear-particle induced osteolysis via modulating Chemerin/ChemR23 and SIRT1 signaling pathway and its bioimaging application

Fig. 8

PCDs suppressed the UHMWPE-induced osteoclastogenesis through Chemerin/ChemR23 signaling and NFATc1 pathway. a Graph representing the relative expression level of osteoclastogenesis-related genes in the experimental groups, which were analyzed using qPCR analysis. b Representative western blot images of proteins and (c) their relative gray levels corresponding to Chem, ChemR23, NFATc1, Itgb3, ACP5, CtsK, and β-actin. Data are represented as mean ± SD; Error bars stand for how much errors are happened during the experiments. * indicates P < 0.05 compared with normal control and # indicates P < 0.05 compared with the UHMWPE group to PCD-treated group

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Journal of Nanobiotechnology

ISSN: 1477-3155

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