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Fig. 9 | Journal of Nanobiotechnology

Fig. 9

From: Photoluminescent carbon dots (PCDs) from sour apple: a biocompatible nanomaterial for preventing UHMWPE wear-particle induced osteolysis via modulating Chemerin/ChemR23 and SIRT1 signaling pathway and its bioimaging application

Fig. 9

PCDs also improve the expression of SIRT1 for reducing the UHMWPE-induced osteoclastogenesis. a Representative western blot images of SIRT1 expression and (b) their relative gray level in the experimental groups. c Representative fluorescence microscope images of SIRT1/DAPI stained osteoclasts, which showing the expression level of SIRT1 in the form of red flourescence. Data are represented as mean ± SD; * indicates P < 0.05 compared with normal control and # indicates P < 0.05 compared with the UHMWPE group to PCD-treated group

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Journal of Nanobiotechnology

ISSN: 1477-3155

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