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Fig. 1 | Journal of Nanobiotechnology

Fig. 1

From: Multistage nucleic acid amplification induced nano-aggregation for 3D hotspots-improved SERS detection of circulating miRNAs

Fig. 1

Characterization of AuNP aggregation induced by HCR. A UV–Vis absorption spectra of AuNPs: a mixture of AuNPs-hp1 and AuNPs-hp2, and miRNA with AuNPs-hp1 and AuNPs-hp. B Dynamic light scattering spectra of AuNPs: a mixture of AuNPs-hp1 and AuNPs-hp2, and miRNA with AuNPs-hp1 and AuNPs-hp. C Agarose gel electrophoresis, Lanes 1–5: AuNP, AuNP-hp1, AuNP-hp2, AuNP-hp1 + AuNP-hp2, and AuNP-hp1 + AuNP-hp2 + miRNA, respectively. D TEM image of the self-grown products

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