Fig. 8

A Fluorescent images of MC3T3-E1 cells treated with different concentrations of FDCDs for 12 and 36 h. Red is actin filaments stained by TRITC–phalloidin staining, and blue is the nucleus visualized by DAPI. B The density and C elongation of MC3T3-E1 cells after co-cultured with FDCDs for 12 and 36 h. D Bright-field images of migrated RAW 264.7 cells incubated without or with 3 mg/mL FDCDs (scale bar, 200 μm). E Chemotaxis index of RAW 264.7 cells. Data are mean ± SD (n = 3) (ns no significance, *p < 0.05, ***p < 0.001)