Differentiated kidney tubular cell-derived extracellular vesicles enhance maturation of tubuloids

Lindoso, Rafael Soares; Yousef Yengej, Fjodor A.; Voellmy, Franziska; Altelaar, Maarten; Mancheño Juncosa, Estela; Tsikari, Theano; Ammerlaan, Carola M. E.; Van Balkom, Bas W. M.; Rookmaaker, Maarten B.; Verhaar, Marianne C.; Masereeuw, Rosalinde

doi:10.1186/s12951-022-01506-6

Journal of Nanobiotechnology

Table 1 Top 50 proteins most expressed in the EVs identified in the EVpedia database

From: Differentiated kidney tubular cell-derived extracellular vesicles enhance maturation of tubuloids

Index	Gene	Protein name	Identified	Index	Gene	Protein name	Identified
1	PDCD6IP	Programmed cell death 6-interacting protein	399	26	MSN	Zinc finger protein MSN2	266
2	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase	377	27	ATP1A1	Na(+)/K(+) ATPase alpha-1 subunit	266
3	HSPA8	Heat shock cognate 71 kDa protein	363	28	PRDX1	Peroxiredoxin-1	263
4	ACTB	Actin, cytoplasmic 1	350	29	MYH9	Myosin-9	262
5	ANXA2	Annexin A2	337	30	EZR	Ezrin	262
6	CD9	CD9 antigen	328	31	CD81	CD81 antigen	262
7	PKM	Pyruvate kinase muscle isozyme	327	32	ANXA6	Annexin A6	260
8	HSP90AA1	Heat shock protein HSP 90-alpha	327	33	FLOT1	Flotillin-1	259
9	ENO1	Alpha-enolase	327	34	YWHAB	14-3-3 protein beta/alpha	258
10	ANXA5	Annexin A5	313	35	LDHB	L-lactate dehydrogenase B chain	258
11	HSP90AB1	Heat shock protein HSP 90-beta	306	36	SLC3A2	4F2 cell-surface antigen heavy chain	257
12	CD63	CD63 antigen	306	37	GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	257
13	YWHAZ	14-3-3 protein zeta/delta	301	38	PFN1	Profilin-1	256
14	YWHAE	14-3-3 protein epsilon	300	39	TSG101	Tumor susceptibility gene 101 protein	255
15	EEF1A1	Elongation factor 1-alpha 1	295	40	YWHAQ	14-3-3 protein theta	254
16	PGK1	Phosphoglycerate kinase 1	291	41	GNAI2	Guanine nucleotide-binding protein G(i) subunit alpha-2	252
17	CLTC	Clathrin heavy chain 1	283	42	CLIC1	Chloride intracellular channel protein 1	251
18	PPIA	Peptidyl-prolyl cis–trans isomerase A	278	43	ANXA1	Annexin A1	251
19	SDCBP	Syntenin-1	277	44	ITGB1	Integrin beta-1	250
20	ALDOA	Fructose-bisphosphate aldolase A	275	45	LDHA	L-lactate dehydrogenase A chain	249
21	EEF2	Protein-lysine N-methyltransferase EEF2KMT	274	46	FASN	Type I Fatty Acid Synthase	248
22	ALB	Albumin	274	47	CDC42	CDC42 small effector	248
23	TPI1	Triosephosphate isomerase	270	48	RAP1B	Ras-related protein Rap-1b	242
24	VCP	Transitional endoplasmic reticulum ATPase	269	49	CCT2	T-complex protein 1 subunit beta	242
25	CFL1	Cofilin-1	268	50	YWHAG	14-3-3 protein gamma	240

Back to article page

ISSN: 1477-3155

Contact us

Submission enquiries: journalsubmissions@springernature.com