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Table 1 Top 50 proteins most expressed in the EVs identified in the EVpedia database

From: Differentiated kidney tubular cell-derived extracellular vesicles enhance maturation of tubuloids

Index Gene Protein name Identified Index Gene Protein name Identified
1 PDCD6IP Programmed cell death 6-interacting protein 399 26 MSN Zinc finger protein MSN2 266
2 GAPDH Glyceraldehyde-3-phosphate dehydrogenase 377 27 ATP1A1 Na(+)/K(+) ATPase alpha-1 subunit 266
3 HSPA8 Heat shock cognate 71 kDa protein 363 28 PRDX1 Peroxiredoxin-1 263
4 ACTB Actin, cytoplasmic 1 350 29 MYH9 Myosin-9 262
5 ANXA2 Annexin A2 337 30 EZR Ezrin 262
6 CD9 CD9 antigen 328 31 CD81 CD81 antigen 262
7 PKM Pyruvate kinase muscle isozyme 327 32 ANXA6 Annexin A6 260
8 HSP90AA1 Heat shock protein HSP 90-alpha 327 33 FLOT1 Flotillin-1 259
9 ENO1 Alpha-enolase 327 34 YWHAB 14-3-3 protein beta/alpha 258
10 ANXA5 Annexin A5 313 35 LDHB L-lactate dehydrogenase B chain 258
11 HSP90AB1 Heat shock protein HSP 90-beta 306 36 SLC3A2 4F2 cell-surface antigen heavy chain 257
12 CD63 CD63 antigen 306 37 GNB1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 257
13 YWHAZ 14-3-3 protein zeta/delta 301 38 PFN1 Profilin-1 256
14 YWHAE 14-3-3 protein epsilon 300 39 TSG101 Tumor susceptibility gene 101 protein 255
15 EEF1A1 Elongation factor 1-alpha 1 295 40 YWHAQ 14-3-3 protein theta 254
16 PGK1 Phosphoglycerate kinase 1 291 41 GNAI2 Guanine nucleotide-binding protein G(i) subunit alpha-2 252
17 CLTC Clathrin heavy chain 1 283 42 CLIC1 Chloride intracellular channel protein 1 251
18 PPIA Peptidyl-prolyl cis–trans isomerase A 278 43 ANXA1 Annexin A1 251
19 SDCBP Syntenin-1 277 44 ITGB1 Integrin beta-1 250
20 ALDOA Fructose-bisphosphate aldolase A 275 45 LDHA L-lactate dehydrogenase A chain 249
21 EEF2 Protein-lysine N-methyltransferase EEF2KMT 274 46 FASN Type I Fatty Acid Synthase 248
22 ALB Albumin 274 47 CDC42 CDC42 small effector 248
23 TPI1 Triosephosphate isomerase 270 48 RAP1B Ras-related protein Rap-1b 242
24 VCP Transitional endoplasmic reticulum ATPase 269 49 CCT2 T-complex protein 1 subunit beta 242
25 CFL1 Cofilin-1 268 50 YWHAG 14-3-3 protein gamma 240