Fig. 7

The impact of PEP@GO-sEVs and PVT1 on HUVEC functionality. HUVECs were randomly distributed into four groups with different treatments. A EDU incorporation assays, B tube formation assays, C transwell migration assays and D its statistical data, E–H cell cycle distribution and rates of apoptosis by flow cytometry, I Western Blotting results of key proteins such as PI3Kγ, PIK3R1, P-Akt, IL-17 and J its statistical data, K qPCR results of relative miR-21-5p and PVT1 level, scale bar: 100 μm. *p < 0.05, **p < 0.01, ***p < 0.001