Skip to main content
Fig.9 | Journal of Nanobiotechnology

Fig.9

From: Protein nanoparticle-induced osmotic pressure gradients modify pulmonary edema through hyperpermeability in acute respiratory distress syndrome

Fig.9

Application of drug combinations after AngII or BK-induced pulmonary edema in vivo. A Pulmonary wet to dry (W/D) ratio. B The level of caspase-1 activity significantly decreased in the serum of the drug combination group compared with that in the AngII or BK group. C Histology of pulmonary sections with hematoxylin and eosin staining from mice challenged with AngII or BK, which was significantly reversed after drug combination treatment. D IHC analyses of pulmonary tissue subjected to control, AngII (100 μg/kg) or BK (100 μg/kg), AngII or BK with drug combination stimulation. The cytoplasm was stained using caspase-1 antibodies (brown). Scale bar: 100 μm. Average of ≥ 5 experiments ± SEM. ns, p > 0.05, **p < 0.01, ***p < 0.001

Back to article page