Fig. 7

Localization of NLRP3 and effects of SDP@Cur-CRT/QSH treatment on NLRP3 and ASC expression in hippocampus and cortex. A Location of NLRP3 in hippocampus and cortex area and relationship with microglia, astrocyte, neuron, and β-amyloid plaques labeled with Iba1, GFAP, NeuN, and 6E10 respectively. B NLRP3 and ASC expression in hippocampus and cortex area in SDP@Cur-CRT/QSH and PBS treated mice (TG). C, D Quantitative analysis of area occupied by NLRP3 and ASC in the SDP@Cur-CRT/QSH group and TG group both in hippocampus and cortex area. *p < 0.05, **p < 0.01, ***p < 0.001