Fig. 3
From: pH-sensitive packaging of cationic particles by an anionic block copolymer shell
Size and surface charge measurements of shielded PBMD (pDNA) particles. A The scheme presents the formulation process of PNC shielded PBMD (pDNA) nanoparticles. B Shielded particles (PBMD + PNC) at varying molar ratios were characterized in terms of diameter (z-average) and polydispersity (PDI) by DLS in comparison to the control polymers (PBMD + PNAM, PBMD + PCEAm). Striped bars mark the occurrence of large aggregates (≥ 1000 nm) that were taken into account as 1000 nm to determine the mean value. The gray area indicates the desired size range (≤ 200 nm) and the dashed line the indicates the PDI value obtained for naked PBMD(pDNA) particles (0.26) (mean of n = 3 ± SD). C The particles were further characterized in terms of surface charge (zeta potential, mean of n = 3 ± SD)