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Fig. 1 | Journal of Nanobiotechnology

Fig. 1

From: Light triggered release of a triple action porphyrin-cisplatin conjugate evokes stronger immunogenic cell death for chemotherapy, photodynamic therapy and cancer immunotherapy

Fig. 1

Characterization and intracellular uptake of NP@Pt-1. A Photograph images of aqueous solution of NP@Pt-1 and TEM images of NP@Pt-1. Scale bar: 500 nm. B Diameter of NP@Pt-1 in water. C UV–vis spectra of porphyrin, Pt-1, and NP@Pt-1. D CLSM images of CT26 murine colon cancer cells treated with Cy5.5 labeled NP@Pt-1 at 1 h, 4 h, and 7 h respectively. Scale bar = 20 μm. E Endocytosis of Cy5.5 labeled NP@Pt-1 by CT26 cells via flow cytometry at 1 h, 4 h and 7 h respectively. F Quantification of the intracellular uptake of Cy5.5 labeled NP@Pt-1 in (E). G ICP-MS quantification of intracellular Pt uptake by CT26 cells exposed to various Pt-containing drugs treatment. (n = 3, ***p < 0.001)

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Journal of Nanobiotechnology

ISSN: 1477-3155

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